Correlation of serum ferritin level in transfusion-dependant thalassemia major patients: a study at a medical college affiliated hospital in Gujarat region

Background: Beta thalassemia is one of the most common causes inherited disorder in world. In India, around 65000-70000 cases are present currently and every years 9000-10000 new added. Measurement serum ferritin level gives an idea about when to start iron chelation therapy, which will reduce concentration thereby prevents multiple organ damages. Methods: A prospective hospital based study was conducted on 100 children having beta major. These were regularly transfused at our their measured by ELISA assay. Detailed transfusion history demographic profile recorded compared with level. Results analyzed SPSS software Microsoft Excels. Results: study, mean 0-5 year age group was1262 µg/l, 6-10 1963.44µg/l 11-18 2387.43µg/l. On applying ANOVA test, it evident that there a statistically significant correlation between increased increasing patient as well number total blood transfusion. Conclusions: High associated dependency. Serum measurement regular interval helps determining ideal timing therapy dependant thalassemic patients.